THE ALPRAZOLAM DIARIES

Metabolism Alprazolam is extensively metabolized in human beings, largely by cytochrome P450 3A4 (CYP3A4), to 2 big Lively metabolites while in the plasma: 4-hydroxyalprazolam and α-hydroxyalprazolam. The plasma circulation levels of the two active metabolites are less than 4% in the mum or dad. The reported relative potencies in benzodiazepine re